Somatostatin receptor imaging with 111 In - pentetreotide intestinal tract in gastro - and lung neuroendocrine tumors - Impact on targeted treatment
نویسنده
چکیده
econd nge of pharmacological radiolabeled analogue raphic localization of astro-intestinal tract we ical imaging modalities erapeutic management ll lung carcinoma it has been used for the evaluation of somatostatin receptor status and a substantial sive disease, especially when e also describe the radiolabeled 90 or lutetium-177 somatostatin analogue peptides in the treatment the use of In-P for the selection of patients for targeted treat-
منابع مشابه
Sarcoidosis mimicking metastatic carinoid on indium-111 pentetreotide scintigraphy
Carcinoid is a neuroendocrine neoplasm derived from primitive stem cells, occurring most frequently in the alimentary tract. Somatostatin-receptor scintigraphy with indium-111 pentetreotide is a sensitive and noninvasive technique for imaging carcinoid and its metastatic spread. However, nontumoral lesions such as sarcoidosis may also express somatostatin receptors, which may present a diagnost...
متن کاملIncremental diagnostic value and impact on patient management of somatostatin receptor scintigraphy with indium-111-pentetreotide in gastroenteropancreatic neuroendocrine tumors.
OBJECTIVE To evaluate the efficacy of somatostatin analog scintigraphy with indium-111-pentetreotide and its overall impact on management in patients with gastroenteropancreatic neuroendocrine tumors (GEP-NET). SUBJECTS AND METHODS Twenty-two consecutive patients with a proven or clinically suspected GEP-NET with or without proven metastases were imaged at 24 and 48 h after injection of (111)...
متن کاملLocalization of Neuroendocrine Tumors Using Somatostatin Receptor Imaging With Indium-111-Pentetreotide (OctreoScan).
BACKGROUND: Many imaging methods have been used to detect neuroendocrine tumors of the gastrointestinal system. There is no gold standard for identifying the location of primary tumors and their potential metastases, and most conventional imaging techniques cannot detect tumors less than 1.0 cm in size. METHODS: The authors have investigated the use of 111-In-pentetreotide as an imaging agent f...
متن کاملIncremental Diagnostic Value and Impact on Patient Management of Somatostatin Receptor Scintigraphy with Indium-111-Pentetreotide in Gastroenteropancreatic Neuroendocrine Tumors
Objective: To evaluate the efficacy of somatostatin analog scintigraphy with indium-111-pentetreotide and its overall impact on management in patients with gastroenteropancreatic neuroendocrine tumors (GEP-NET). Subjects and Methods: Twenty-two consecutive patients with a proven or clinically suspected GEP-NET with or without proven metastases were imaged at 24 and 48 h after injection of 111 I...
متن کاملTreatment of advanced neuroendocrine tumours with the radiolabelled somatostatin analogue octreotide.
Neuroendocrine tumours (NET) have a particular tendency to express functional receptors and/or uptake mechanisms. Radionuclides, such as (111)In-pentetreotide, a somatostatin analogue, which bind to somatostatin receptors, present an imaging modality that has been used for both the diagnosis and staging of NET. Scintigraphy with (111)In-pentetreotide can identify lesions beyond the diagnostic s...
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